Mayo's 5 year plan is on the city of Rochester's planning and zoning page... here's a list of potential projects to start up that I found interesting (I trimmed down this list by a substantial amount).
East expansion of Mary Brigh Building for diagnostic, treatment and inpatient functions.
Horizontal and vertical expansion of the Generose Building.
Bed tower expansion of East Mary Brigh Building.
Pedestrian skyway from Mary Brigh Building to Generose Building.
Skyway/subway connections north across Second Street and/or west across 14th AvenueSW.
Possible hospital facility expansion east of the Eisenberg Building
Continued expansions/renovations in Charlton, Eisenberg, Colonial & Jacobson Buildings.
Vertical / horizontal expansion of the Jacobson Building.
Renovation/replacement of Charlton North Building.
Phase Three vertical expansion of Gonda Building.
West horizontal expansion of Baldwin Building.
Vertical expansion of Harwick Building.
Major expansion of clinical laboratory, research and education space on Blocks 7 & 12, south of
Hilton/Guggenheim. Initial phases as well as future expansion.
Vertical / horizontal expansion of Opus Building.
New multi-use building and/or expansion of parking on Block 11, North of former Lourdes High School.
Provision for a mixed-use project for patient/staff parking ramp, possibly including education administrative
& utility support – South of Baldwin Building on Block 2.
Subway connection from Dan Abraham Healthy Living Center to Ozmun Building.
http://www.rochestermn.gov/home/showdocument?id=12002